Localized Chemical Reactivity in Double-Stranded DNA Associated with the Intercalative Binding of Benzo[e]Pyridoindole and Benzo[g]Pyridoindole Triple-Helix-Stabilizing Ligands
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چکیده
منابع مشابه
Unwinding of double-stranded DNA helix by dehydration.
Conformation changes of the double-stranded DNA helix in response to dehydration were investigated by monitoring, by agarose gel electrophoresis, the linking number of covalently closed circular DNA generated by ligation of linear DNA in the presence of different organic solvents or different temperatures. It was found that: (i) The DNA helix unwinds upon addition of certain organic solvents or...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1995
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1995.tb20782.x